Biotransformation of beta-endorphin and possible therapeutic implications

  title={Biotransformation of beta-endorphin and possible therapeutic implications},
  author={Naghmeh Hajarol Asvadi and Michael P. Morgan and Amitha K. Hewavitharana and P. N. Shaw and Peter John Cabot},
  booktitle={Front. Pharmacol.},
Endogenous opioid peptides have been aligned with a diverse array of effects. Their activity is not only attributable to action the three main opioid receptors, mu (MOR), delta (DOR), and kappa (KOR) opioid receptors but their impacts appear to extend to activities at sodium channels, cytokine receptors (Finley et al., 2008), calcium channels and non-specific and partially undefined pharmacological effects inconsistent with G-protein coupled opioid receptor activity. Of the family of opioid… CONTINUE READING
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