Biotransformation of a C-glycosylflavone, abrusin 2''-O-beta-D-apioside, by human intestinal bacteria.

@article{Li2000BiotransformationOA,
  title={Biotransformation of a C-glycosylflavone, abrusin 2''-O-beta-D-apioside, by human intestinal bacteria.},
  author={Y L Li and Meselhy Ragab Meselhy and L Q Wang and Chao-Mei Ma and Norio Nakamura and Masao Hattori},
  journal={Chemical & pharmaceutical bulletin},
  year={2000},
  volume={48 8},
  pages={1239-41}
}
After anaerobic incubation of abrusin 2''-O-beta-D-apioside (1) with a human fecal suspension, five metabolites were isolated and identified as abrusin (2), 1-(2',6'-dihydroxy-3',4'-dimethoxyphenyl)-3-(4''-hydroxyphenyl)propan-1- one (5), 5,6-dimethoxybenzene-1,3-diol (6), 3-(4'-hydroxyphenyl)propionic acid (7) and 3-phenylpropionic acid (8). However… CONTINUE READING