Biotinylated recombinant human erythropoietins: bioactivity and utility as receptor ligand.

Abstract

Recombinant human erythropoietin labeled covalently with biotin at sialic acid moieties has been prepared, and has been shown to possess high biological activity plus utility as a receptor ligand. Initially, the effects on biological activity of covalently attaching biotin to erythropoietin alternatively at carboxylate, amino, or sialic acid groups were… (More)

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Cite this paper

@article{Wojchowski1989BiotinylatedRH, title={Biotinylated recombinant human erythropoietins: bioactivity and utility as receptor ligand.}, author={Don M. Wojchowski and Laurie F Caslake}, journal={Blood}, year={1989}, volume={74 3}, pages={952-8} }