Biotinidase deficiency: A novel vitamin recycling defect
@article{Wolf2005BiotinidaseDA, title={Biotinidase deficiency: A novel vitamin recycling defect}, author={B. Wolf and R. E. Grier and J. S. Secor McVoy and G. S. Heard}, journal={Journal of Inherited Metabolic Disease}, year={2005}, volume={8}, pages={53-58} }
The recent finding that biotinidase deficiency is the primary biochemical defect in late-onset multiple carboxylase deficiency has stimulated new interest in the inherited disorders of biotin-dependent carboxylases. The clinical and biochemical features of biotinidase deficiency are discussed. We also speculate about two exciting areas currently being investigated: the localization of action of biotinidase, and the possible role of the enzyme as a binding or carrier protein for biotin.
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