Biotechnology and genetics of ergot alkaloids

@article{Tudzynski2001BiotechnologyAG,
  title={Biotechnology and genetics of ergot alkaloids},
  author={Paul Tudzynski and Telmo Correia and Ulrich Keller},
  journal={Applied Microbiology and Biotechnology},
  year={2001},
  volume={57},
  pages={593-605}
}
Abstract. Ergot alkaloids, i.e. ergoline-derived toxic metabolites, are produced by a wide range of fungi, predominantly by members of the grass-parasitizing family of the Clavicipitaceae. Naturally occurring alkaloids like the D-lysergic acid amides, produced by the "ergot fungus" Claviceps purpurea, have been used as medicinal agents for a long time. The pharmacological effects of the various ergot alkaloids and their derivatives are due to the structural similarity of the tetracyclic ring… 
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