Biosynthetic response of cartilage explants to dynamic compression
@article{Sah1989BiosyntheticRO, title={Biosynthetic response of cartilage explants to dynamic compression}, author={Robert L. Sah and Young-Jo Kim and J. Y. H. Doong and Alan J. Grodzinsky and Anna Plass and John D. Sandy}, journal={Journal of Orthopaedic Research}, year={1989}, volume={7} }
The biosynthetic response of calf articular cartilage explants to dynamic compression was examined over a wide range of amplitudes, waveforms, and frequencies. Glycosaminoglycan synthesis was assessed by 35S‐sulfate incorporation, and amino acid uptake and protein synthesis were assessed by 3H‐proline incorporation. Two culture chambers were designed to allow uniaxial radially unconfined compression and mechanical testing of cartilage disks: one chamber was used inside a standard incubator; the…
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