Biosynthetic pathway of beta-methylnorleucine, an antimetabolite produced by Serratia marcescens.

Abstract

beta-Methylnorleucine biosynthesis was examined in Serratia marcescens using regulatory mutants of branched-chain amino acid biosynthesis. The accumulation of beta-methylnorleucine from norvaline in the wild-type strain was inhibited by the simultaneous additions of isoleucine, valine and leucine, although its accumulation in the derepressed mutant of… (More)

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@article{Sugiura1981BiosyntheticPO, title={Biosynthetic pathway of beta-methylnorleucine, an antimetabolite produced by Serratia marcescens.}, author={Masako Sugiura and Masahiko Kisumi and Ichiro Chibata}, journal={The Journal of antibiotics}, year={1981}, volume={34 10}, pages={1283-9} }