Biosynthetic pathway for acrylic acid from glycerol in recombinant Escherichia coli

Abstract

Acrylic acid is an important industrial feedstock. In this study, a de novo acrylate biosynthetic pathway from inexpensive carbon source glycerol was constructed in Escherichia coli. The acrylic acid was produced from glycerol via 3-hydroxypropionaldehyde, 3-hydroxypropionyl-CoA, and acrylyl-CoA. The acrylate production was improved by screening and site… (More)
DOI: 10.1007/s00253-015-7272-z

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