Biosynthetic Functional Gene Analysis of Bis-Indole Metabolites from 25D7, a Clone Derived from a Deep-Sea Sediment Metagenomic Library

@inproceedings{Yan2016BiosyntheticFG,
  title={Biosynthetic Functional Gene Analysis of Bis-Indole Metabolites from 25D7, a Clone Derived from a Deep-Sea Sediment Metagenomic Library},
  author={Xia Lin Yan and Xi-Xiang Tang and Dan Qin and Zhi-Wei Yi and Mei-Juan Fang and Zhen Wu and Ying-kun Qiu},
  booktitle={Marine drugs},
  year={2016}
}
This work investigated the metabolites and their biosynthetic functional hydroxylase genes of the deep-sea sediment metagenomic clone 25D7. 5-Bromoindole was added to the 25D7 clone derived Escherichia coli fermentation broth. The new-generated metabolites and their biosynthetic byproducts were located through LC-MS, in which the isotope peaks of brominated… CONTINUE READING