Biosynthesis of urea; enzymatic mechanism of arginine synthesis from citrulline.

@article{Ratner1949BiosynthesisOU,
  title={Biosynthesis of urea; enzymatic mechanism of arginine synthesis from citrulline.},
  author={Stuart Ratner and Apostolos Pappas},
  journal={The Journal of biological chemistry},
  year={1949},
  volume={179 3},
  pages={1183-98}
}
In urea synthesis, according to the Krebs-Henseleit ornithine cycle (l), the transfer of nitrogen to citrulline to form arginine (Step II) was thought to occur from NH$. It was not until Cohen and Hayano (2) succeeded in demonstrating rapid arginine synthesis in liver homogenates from glutamic acid and citrulline that the transfer from an amino acid rather than from NH, was recognized as a main pathway in urea formation. Under their conditions, arginine was formed in the presence of oxygen, Mg… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-3 of 3 references

Abstracts, American Chemical Society, Washington

S. Ratner
D. C., • 1948

hp://w w w .jb.org/ D ow nladed from S. Ratner and Anne Pappas CITRULLINE ARGININE SYNTHESIS FROM ENZYMATIC MECHANISM OF BIOSYNTHESIS OF UREA: I

E. Racker
J. BioZ. Chem., • 1947

The nature of the chemical bond

L. Pauling
Ithaca, 2nd edition, • 1940

Similar Papers

Loading similar papers…