Biosynthesis of sucrose-6-acetate catalyzed by surfactant-coated Candida rugosa lipase immobilized on sol–gel supports

@article{Zhong2013BiosynthesisOS,
  title={Biosynthesis of sucrose-6-acetate catalyzed by surfactant-coated Candida rugosa lipase immobilized on sol–gel supports},
  author={X. Zhong and Junqing Qian and H. Guo and Y. Hu and M. Liu},
  journal={Bioprocess and Biosystems Engineering},
  year={2013},
  volume={37},
  pages={813-818}
}
  • X. Zhong, Junqing Qian, +2 authors M. Liu
  • Published 2013
  • Chemistry, Medicine
  • Bioprocess and Biosystems Engineering
  • Sucrose-6-acetate is an important intermediate in the preparation of sucralose (a finest sweetener). In our study, Candida rugosa lipase coated with surfactant was firstly immobilized on sol–gel supports. Then, the immobilized enzyme was used in the regioselective synthesis of sucrose-6-acetate by transesterification of sucrose and vinyl acetate. The screening results revealed that Tween 80 was an ideal surfactant to coat lipase immobilized in sol–gel and exhibited the highest yield of sucrose… CONTINUE READING
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