Biosynthesis of sialic acids by Neisseria meningitidis.

@article{Blacklow1962BiosynthesisOS,
  title={Biosynthesis of sialic acids by Neisseria meningitidis.},
  author={R S Blacklow and L. Patrick Warren},
  journal={The Journal of biological chemistry},
  year={1962},
  volume={237},
  pages={3520-6}
}
Recent reports from this laboratory (2-4) and other laboratories (5, 6) have elucidated the pathway of biosynthesis of N-acetylneuraminic acid from N-acetyl-n-mannosamine and phosphoenolpyruvic acid in mammalian systems. The over-all biosynthetic reaction for rat liver and bovine submaxillary gland is catalyzed by 3 enzymes: a kinase, a condensing enzyme, and a dephosphorylating enzyme. N-Acetyl-n-mannosamine is phosphorylated by a specific kinase and adenosine triphosphate to yield N-acetyl-n… CONTINUE READING
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hp://w w w .jb.org/ D ow nladed from Robert S. Blacklow and Leonard Warren Neisseria meningitidis Biosynthesis of Sialic Acids by 1962, 237:3520-3526

  • L. WABBEN, R. S. BLACKLOW
  • J. Biol. Chem.,
  • 1962

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