Biosynthesis of poly(3-hydroxyalkanoate) from amino acids.

  title={Biosynthesis of poly(3-hydroxyalkanoate) from amino acids.},
  author={Kiyohiko Nakamura and Yoshio Goto and Naoko Yoshie and Yasunori Inoue},
  journal={International journal of biological macromolecules},
  volume={14 6},
It was found that an optically active copolyester, poly(3-hydroxybutyrate-co-3-hydroxyvalerate), denoted as P(3HB-co-3HV), is synthesized by Alcaligenes eutrophus H16 from several amino acids under various fermentation conditions. The optimum condition for the biosynthesis from one amino acid, threonine, was investigated and its biosynthetic pathway was discussed on the basis of the relation between the fermentation condition and the co-monomer composition of the produced polyesters.