Biosynthesis of nectrisine in Thelonectria discophora SANK 18292.

@article{Miyauchi2015BiosynthesisON,
  title={Biosynthesis of nectrisine in Thelonectria discophora SANK 18292.},
  author={R. Miyauchi and T. Takatsu and Tetsuya Suzuki and Y. Ono and Y. Shiba},
  journal={Phytochemistry},
  year={2015},
  volume={116},
  pages={
          87-93
        }
}
Nectrisine, an iminosugar with a heterocyclic nitrogen-containing 5-membered ring, acts as a glycosidase inhibitor. Thelonectria discophora SANK 18292, a fungus, was identified as a nectrisine producer from its microbial library in our screening for nectrisine producing microorganisms. Biosynthesis of nectrisine produced by the fungus was studied using stable isotope tracer techniques. Incorporation of (13)C-labeled d-ribose and d-xylose into nectrisine was confirmed by mass spectrometry and… Expand
3 Citations
Nectrisine Biosynthesis Genes in Thelonectria discophora SANK 18292: Identification and Functional Analysis
Characterization of a novel oxidase from Thelonectria discophora SANK 18292 involved in nectrisine biosynthesis

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