Biosynthesis of iron-sulphur clusters is a complex and highly conserved process.

  title={Biosynthesis of iron-sulphur clusters is a complex and highly conserved process.},
  author={Jeverson Frazzon and James R Fick and Dennis R Dean},
  journal={Biochemical Society transactions},
  volume={30 4},
Iron-sulphur ([Fe-S]) clusters are simple inorganic prosthetic groups that are contained in a variety of proteins having functions related to electron transfer, gene regulation, environmental sensing and substrate activation. In spite of their simple structures, biological [Fe-S] clusters are not formed spontaneously. Rather, a consortium of highly conserved proteins is required for both the formation of [Fe-S] clusters and their insertion into various protein partners. Among the [Fe-S] cluster… CONTINUE READING

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