Biosynthesis of ether-type polar lipids in archaea and evolutionary considerations.

  title={Biosynthesis of ether-type polar lipids in archaea and evolutionary considerations.},
  author={Yosuke Koga and Hiroyuki Morii},
  journal={Microbiology and molecular biology reviews : MMBR},
  volume={71 1},
This review deals with the in vitro biosynthesis of the characteristics of polar lipids in archaea along with preceding in vivo studies. Isoprenoid chains are synthesized through the classical mevalonate pathway, as in eucarya, with minor modifications in some archaeal species. Most enzymes involved in the pathway have been identified enzymatically and/or genomically. Three of the relevant enzymes are found in enzyme families different from the known enzymes. The order of reactions in the… CONTINUE READING
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