Biosynthesis of docosahexaenoate-containing glycerolipid molecular species in the retina

@article{Li2001BiosynthesisOD,
  title={Biosynthesis of docosahexaenoate-containing glycerolipid molecular species in the retina},
  author={Feng Li and Huiming Chen and Robert E. Anderson},
  journal={Journal of Molecular Neuroscience},
  year={2001},
  volume={16},
  pages={205-214}
}
Vertebrate retinas are highly enriched in long-chain polyunsaturated fatty acids (PUFA), especially docosahexaenoic acid (22:6n-3, DHA). In the present study, we investigated the role of de novo synthesis in the enrichment of 22:6n-3 in characteristic molecular species of retinal glycerolipids. Following the incubation of fresh dark-adapted retinas with [2-3H]-glycerol, individual glycerolipids were isolated and converted into either diacylglycerol acetates (DGAC) or diacylglycerol benzoates… CONTINUE READING

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