Biosynthesis of docosahexaenoate-containing glycerolipid molecular species in the retina

  title={Biosynthesis of docosahexaenoate-containing glycerolipid molecular species in the retina},
  author={Feng Li and Huiming Chen and Robert E. Anderson},
  journal={Journal of Molecular Neuroscience},
Vertebrate retinas are highly enriched in long-chain polyunsaturated fatty acids (PUFA), especially docosahexaenoic acid (22:6n-3, DHA). In the present study, we investigated the role of de novo synthesis in the enrichment of 22:6n-3 in characteristic molecular species of retinal glycerolipids. Following the incubation of fresh dark-adapted retinas with [2-3H]-glycerol, individual glycerolipids were isolated and converted into either diacylglycerol acetates (DGAC) or diacylglycerol benzoates… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 34 references

Lipid biochemistry: functions of glycerolipids and sphingolipids in cellular signaling.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 1997
View 1 Excerpt

Glycerolipid biosynthesis in eukaryotes, in new comprehensive biochemistry, in Biochemistry of Lipids, Lipoproteins, and Membranes

D E.Vance

Effect of dietary n-3 fatty acids upon the phospholipid molecular species of the monkey retina

D S.Lin, G J.Anderson, W E.Connor, M. Neuringer
Invest. Ophthalmol. Vis. Sci • 1994

Biological function of docosahexaenoic acid in the retina rod disk membrane , in The Third International Congress on Essential Fatty Acid and Eicosanoids (

F. BrownM., J. GibsonN.

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