• DOI:10.1007/PL00000670
Corpus ID: 583311

Biosynthesis of cobalamin (vitamin B12): a bacterial conundrum

@article{Raux2000BiosynthesisOC,
  title={Biosynthesis of cobalamin (vitamin B12): a bacterial conundrum
},
  author={E. Raux and H. L. Schubert and M. Warren},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={2000},
  volume={57},
  pages={1880-1893}
}

E. Raux, H. L. Schubert, M. Warren

Published 2000

Biology, Medicine

Cellular and Molecular Life Sciences CMLS

Abstract. The biosynthesis of cobalamin (vitamin B12) is described, revealing how the concerted action of around 30 enzyme-mediated steps results in the synthesis of one of Nature's most structurally complex ‘small molecules’. The plethora of genome sequences has meant that bacteria capable of cobalamin synthesis can be easily identified and their biosynthetic genes compared. Whereas only a few years ago cobalamin synthesis was thought to occur by one of two routes, there are apparently a… CONTINUE READING

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