Biosynthesis of Trehangelin in Polymorphospora rubra K07-0510: Identification of Metabolic Pathway to Angelyl-CoA.

@article{Inahashi2016BiosynthesisOT,
  title={Biosynthesis of Trehangelin in Polymorphospora rubra K07-0510: Identification of Metabolic Pathway to Angelyl-CoA.},
  author={Yuki Inahashi and Taro Shiraishi and Kaia Palm and Yoko Takahashi and Satoshi O̅mura and Tomohisa Kuzuyama and Takuji Nakashima},
  journal={Chembiochem : a European journal of chemical biology},
  year={2016},
  volume={17 15},
  pages={1442-7}
}
Trehangelins are trehalose angelates discovered from endophytic actinomycete Polymorphospora rubra K07-0510. We identified the trehangelin biosynthetic gene cluster, including genes that encode a glycoside hydrolase-like protein (thgC), α-amylase (thgD), 3-ketoacyl-ACP synthase III (thgI), 3-ketoacyl-ACP reductase (thgK), enoyl-CoA hydratase (thgH) and acyl… CONTINUE READING