Biosynthesis of 5-hydroxy-L-tryptophan by a genetically modified strain ofEscherichia coli in presence of 5-hydroxyindole

@article{Skogman2005BiosynthesisO5,
  title={Biosynthesis of 5-hydroxy-L-tryptophan by a genetically modified strain ofEscherichia coli in presence of 5-hydroxyindole},
  author={G. S. Skogman and J. E. Sj{\"o}str{\"o}m},
  journal={Biotechnology Letters},
  year={2005},
  volume={7},
  pages={783-788}
}
A derivative ofEscherichia coli strain W3110 with increased tryptophan synthas (TS) activity was studied in the biosynthesis of L-tryptophan and 5-hydroxy-L-tryptophan, respectively, in presence of precursors. Indole or 5-hydroxyindole was added to growing cells in minimal medium supplemented with tetracycline. The specific activity of TS for 5… CONTINUE READING