Biosynthesis of 3β‐hydroxy‐5,7‐pregnadien‐20‐one by the horse fetal gonad

  title={Biosynthesis of 3$\beta$‐hydroxy‐5,7‐pregnadien‐20‐one by the horse fetal gonad},
  author={Alexander D. Tait and L. C. Hodge and W. Ross Allen},
  journal={FEBS Letters},

Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives.

  • M. ŻmijewskiWei Li A. Slominski
  • Biology
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
  • 2008
Calcitriol (3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-1alpha,3beta,25-triol) is a powerful oncostatic form of vitamin D3 that is of limited clinical utility due to hypercalcemic (toxic)

Novel activities of CYP11A1 and their potential physiological significance

Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes.

Immunohistochemical localization of oestrogen receptors alpha and beta, progesterone receptor and aromatase in the equine placenta.

The detection of ERalpha, ERbeta and PR in foetal and maternal vascular tissue suggests that placental steroids are also involved in the control of placental angiogenesis and /or vascular functions.



Aromatization of delta-7-C19-steroids to delta-7-estrogens by human placenta in vitro.

The results indicate a lack of capacity to introduce a Δ7-bond into estrogens and their Δ4- or Δ5-C19 precursors and the following characteristics of the placental preparation used: capacity to aromatize Δ4,7-and Δ5,7 -C19-precursors without affecting the Δ7 -bond.

In vivo biosynthesis of steroids from tyrosine.

The conversion of 23,24-dinor-chol-5-en-3 -ol into steroid hormones.

  • A. Tait
  • Chemistry
    The Biochemical journal
  • 1972
It is widely accepted that cholesterol is the precursor of the steroid hormones. However, there are reports suggesting that there could be some other pathway not involving cholesterol (Heard et al.,

Chromatography of Steroids

The Chromatography of Steroids by Prof. I. E. Bush is described on net.

Hoppe - Seyler ’ s Z

  • Physiol . Chem .
  • 1966