Biosynthesis and secretion of recombinant human growth hormone in Pichia pastoris

Abstract

Mature human growth hormone (hGH) cDNA was cloned by homologous recombination into the yeast Pichia pastoris genome. The hGH gene expression was placed under the control of the methanol-inducible alcohol oxidase 1 (AOX1) gene promoter and the Saccharomyces cerevisiae α-factor signal sequence to direct the secretion of recombinant human growth hormone (rhGH… (More)
DOI: 10.1023/A:1005675920451

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@article{EcamillaTrevio2004BiosynthesisAS, title={Biosynthesis and secretion of recombinant human growth hormone in Pichia pastoris}, author={L. L. Ecamilla-Trevi{\~n}o and Jos{\'e} Mar{\'i}a Viader-Salvad{\'o} and Hugo Alberto Barrera-Salda{\~n}a and Martha Guerrero-Olazar{\'a}n}, journal={Biotechnology Letters}, year={2004}, volume={22}, pages={109-114} }