Biosynthesis and regulation of superoxide dismutases.

@article{Hassan1988BiosynthesisAR,
  title={Biosynthesis and regulation of superoxide dismutases.},
  author={H. Moustafa Hassan},
  journal={Free radical biology & medicine},
  year={1988},
  volume={5 5-6},
  pages={
          377-85
        }
}
The past two decades have witnessed an explosion in our understanding of oxygen toxicity. The discovery of superoxide dismutases (SODs) (EC.1.15.1.1), which specifically catalyze the dismutation of superoxide radicals (O2-) to hydrogen peroxide (H2O2) and oxygen, has indicated that O2- is a normal and common byproduct of oxygen metabolism. There is an increasing evidence to support the conclusion that superoxide radicals play a major role in cellular injury, mutagenesis, and many diseases. In… CONTINUE READING
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