Biosynthesis and insertion of Wolfgram protein into optic nerve membranes

Abstract

Antibodies against pig brain Wolfgram protein (WP) were prepared and utilized in the analysis of WP biosynthesis in membranes from optic nerves of 20 day-old rats. Newly synthesized WP appeared rapidly (<5 min) in myelin and in a non-myelin microsome fraction and accumulated in both thereafter. Monensin did not affect the insertion of WP in either membrane… (More)
DOI: 10.1007/BF00964627

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