Biosynthesis, Maturation, Release, and Degradation of Neurotensin and Neuromedin N

@article{Kitabgi1992BiosynthesisMR,
  title={Biosynthesis, Maturation, Release, and Degradation of Neurotensin and Neuromedin N},
  author={P. Kitabgi and F. Nadai and C. Rov{\`e}re and J. Bidard},
  journal={Annals of the New York Academy of Sciences},
  year={1992},
  volume={668}
}
The cloning in 1987 of the neurotensin (NT) precursor' has revealed that it contains several possible dibasic maturation sites, and therefore has the capability to generate a number of different peptides, two of them being the biologically active peptides NT, the focus of this volume, and neuromedin N (NN), a NT-related peptide that was isolated in 1984 from porcine spinal cord' (see also the two preceding chapters of this volume). In order to understand the physiology of the NT/NN producing… Expand
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