Bioreactors for connective tissue engineering: design and monitoring innovations.

@article{Haj2009BioreactorsFC,
  title={Bioreactors for connective tissue engineering: design and monitoring innovations.},
  author={A. J. El Haj and Karen Hampson and Ga{\"e}tan Gogniat},
  journal={Advances in biochemical engineering/biotechnology},
  year={2009},
  volume={112},
  pages={81-93}
}
The challenges for the tissue engineering of connective tissue lie in creating off-the-shelf tissue constructs which are capable of providing organs for transplantation. These strategies aim to grow a complex tissue with the appropriate mechanical integrity necessary for functional load bearing. Monolayer culture systems lack correlation with the in vivo environment and the naturally occur ring cell phenotypes. Part of the development of more recent models is to create growth environments or… CONTINUE READING