Bioproduction of p-hydroxystyrene from glucose by the solvent-tolerant bacterium Pseudomonas putida S12 in a two-phase water-decanol fermentation.

@article{Verhoef2009BioproductionOP,
  title={Bioproduction of p-hydroxystyrene from glucose by the solvent-tolerant bacterium Pseudomonas putida S12 in a two-phase water-decanol fermentation.},
  author={Suzanne Verhoef and Nick J. P. Wierckx and R. G. Maaike Westerhof and Johannes H. De Winde and Harald J. Ruijssenaars},
  journal={Applied and environmental microbiology},
  year={2009},
  volume={75 4},
  pages={931-6}
}
Two solvent-tolerant Pseudomonas putida S12 strains, originally designed for phenol and p-coumarate production, were engineered for efficient production of p-hydroxystyrene from glucose. This was established by introduction of the genes pal and pdc encoding L-phenylalanine/L-tyrosine ammonia lyase and p-coumaric acid decarboxylase, respectively. These enzymes allow the conversion of the central metabolite L-tyrosine into p-hydroxystyrene, via p-coumarate. Degradation of the p-coumarate… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 37 extracted citations

Pseudomonas putida—a versatile host for the production of natural products

Applied Microbiology and Biotechnology • 2015
View 4 Excerpts
Highly Influenced

Bio-based production of C2-C6 platform chemicals.

Biotechnology and bioengineering • 2012
View 1 Excerpt
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Transcriptome analysis of a phenol-producing Pseudomonas putida S12 construct: genetic and physiological basis for improved production

N.J.P. Wierckx, H. Ballerstedt, +3 authors J. Wery
J. Bacteriol • 2008

Similar Papers

Loading similar papers…