Bioprocess development for production, purification, and structural characterization of recombinant hCD83ext as a potential therapeutic protein.

Abstract

An effective bioprocess for the production of hCD83ext (i.e. the extracytoplasmic domain of human CD83) as a potential therapeutic protein was developed. It primarily consists of (1) cell cultivation for the production of recombinant glutathione-S-transferase-hCD83ext (GST-hCD83ext) fusion protein and (2) downstream processing for purification of hCD83ext… (More)
DOI: 10.1016/j.pep.2008.12.005

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@article{Xu2009BioprocessDF, title={Bioprocess development for production, purification, and structural characterization of recombinant hCD83ext as a potential therapeutic protein.}, author={Yali Xu and Lin Zhang and Weifang Yao and Shreyas S Yedahalli and Stephen J. Brand and Murray Moo-Young and C Perry Chou}, journal={Protein expression and purification}, year={2009}, volume={65 1}, pages={92-9} }