Bioprocess development for nicotinic acid hydroxamate synthesis by acyltransferase activity of Bacillus smithii strain IITR6b2

@article{Agarwal2013BioprocessDF,
  title={Bioprocess development for nicotinic acid hydroxamate synthesis by acyltransferase activity of Bacillus smithii strain IITR6b2},
  author={Shilpi Agarwal and Meenu Gupta and Bijan Choudhury},
  journal={Journal of Industrial Microbiology & Biotechnology},
  year={2013},
  volume={40},
  pages={937-946}
}
In this work, acyltransferase activity of a new bacterial isolate Bacillus smithii strain IITR6b2 was utilized for the synthesis of nicotinic acid hydroxamate (NAH), a heterocyclic class of hydroxamic acid. NAH is an important pyridine derivative and has found its role as bioligand, urease inhibitor, antityrosinase, antioxidant, antimetastatic, and vasodilating agents. Amidase having acyltransferase activity with nicotinamide is suitable for nicotinic acid hydroxamate production. However… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 24 references

Study of the acyl transfer activity of a recombinant amidase overproduced in an Escherichia coli Strain. Application for short-chain hydroxamic acid and acid hydrazide synthesis

  • D Fournand, A Arnaud, P Galzy
  • J Mol Cata B: Enzym
  • 1998
Highly Influential
6 Excerpts

Effects of nicotinic acid derivatives on tyrosinase inhibitory and antioxidant activities

  • YS Lin, SH Chen, +4 authors WC Hou
  • Food Chem
  • 2012
1 Excerpt

Biotransformation of nitriles to hydroxamic acids via a nitrile hydratase-amidase cascade reaction

  • V Vejvoda, L Marti 9nková, +4 authors B Uhnáková
  • J Mol Cata B: Enzym
  • 2011
1 Excerpt

County T (2011) Method for scavenging free radicals and inhibiting tyrosinase and melanin

  • CH Chen, T County, +4 authors YH Lin
  • US 2011/00339898A1
  • 2011
2 Excerpts

Crystal structure of a novel heterobi - metallic 3 - pyridinehydroxamate - bridged Pt ( II ) / Cu ( II ) wave - like coordination polymer

  • A Ohtaki, K Murata, +6 authors M Odaka
  • 2010

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