Biophysics of mechanoreception.

  title={Biophysics of mechanoreception.},
  author={Frederick Sachs},
  journal={Membrane biochemistry},
  volume={6 2},
Several types of cells' skeletal, muscle, nerve, epithelia, and heart have been shown to contain ion channels which are sensitive to membrane tension. In chick skeletal muscle, the transduction persists in excised patches and involves no chemical messengers. Quantitative analysis of single channel records reveals that the sensitivity to stretch can be described by a linear four state model with three closed (C) and one open (O) state: (Formula: see text). Only the rate constant k12 is sensitive… CONTINUE READING

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