• Corpus ID: 90261121

Biophysics-based critique of the assisted discharge mechanism hypothesis

@article{Stern2019BiophysicsbasedCO,
  title={Biophysics-based critique of the assisted discharge mechanism hypothesis},
  author={Julie V. Stern and Thiruvallur R. Gowrishankar and Kyle C. Smith and James C. Weaver},
  journal={arXiv: Biological Physics},
  year={2019}
}
Cell experiments with large, short electric field pulses of opposite polarity reveal a remarkable phenomenon: Bipolar cancellation (BPC). Typical defining experiments involve quantitative observation of tracer molecule influx at times of order 100 s post pulsing. Gowrishankar et al. BBRC 2018 503:1194-1199 shows that long-lived pores and altered partitioning or hindrance due to inserted occluding molecules can account for BPC. In stark contrast, the Assisted Discharge (AD) hypothesis, Pakhomov… 

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