Biophysically Based Modeling of the Interstitial Cells of Cajal: Current Status and Future Perspectives

  title={Biophysically Based Modeling of the Interstitial Cells of Cajal: Current Status and Future Perspectives},
  author={Rachel Lees-Green and Peng Du and Gregory O’Grady and Arthur Beyder and Gianrico Farrugia and Andrew J. Pullan},
  booktitle={Front. Physio.},
Gastrointestinal motility research is progressing rapidly, leading to significant advances in the last 15 years in understanding the cellular mechanisms underlying motility, following the discovery of the central role played by the interstitial cells of Cajal (ICC). As experimental knowledge of ICC physiology has expanded, biophysically based modeling has become a valuable tool for integrating experimental data, for testing hypotheses on ICC pacemaker mechanisms, and for applications in in… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 17 extracted citations


Publications referenced by this paper.
Showing 1-10 of 140 references

Quantitative cellular description of gastric slow wave activity.

American journal of physiology. Gastrointestinal and liver physiology • 2008
View 20 Excerpts
Highly Influenced

A Model of Slow Wave Propagation and Entrainment Along the Stomach

Annals of Biomedical Engineering • 2010
View 5 Excerpts
Highly Influenced

In situ recording from gut pacemaker cells

Pflügers Archiv - European Journal of Physiology • 2008
View 9 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…