Biophysically Based Modeling of the Interstitial Cells of Cajal: Current Status and Future Perspectives

@inproceedings{LeesGreen2011BiophysicallyBM,
  title={Biophysically Based Modeling of the Interstitial Cells of Cajal: Current Status and Future Perspectives},
  author={Rachel Lees-Green and Peng Du and Gregory O’Grady and Arthur Beyder and Gianrico Farrugia and Andrew J. Pullan},
  booktitle={Front. Physio.},
  year={2011}
}
Gastrointestinal motility research is progressing rapidly, leading to significant advances in the last 15 years in understanding the cellular mechanisms underlying motility, following the discovery of the central role played by the interstitial cells of Cajal (ICC). As experimental knowledge of ICC physiology has expanded, biophysically based modeling has become a valuable tool for integrating experimental data, for testing hypotheses on ICC pacemaker mechanisms, and for applications in in… CONTINUE READING

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