Biophysical properties of a chloride channel in the apical membrane of a secretory epithelial cell.

Abstract

1. Patch clamp studies on colonic tumor cell line T84 show the presence of chloride channels. 2. The channels are activated by forskolin, PGE2, or 8-Br-cAMP. 3. Single channel conductance was ca 40 pS at the reversal potential, increasing to 70 pS at +80 mV and decreasing to 25 pS at -80 mV. 4. Relative permeabilities were I greater than Br greater than Cl… (More)

Topics

Statistics

0100200'93'96'99'02'05'08'11'14'17
Citations per Year

180 Citations

Semantic Scholar estimates that this publication has 180 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Halm1988BiophysicalPO, title={Biophysical properties of a chloride channel in the apical membrane of a secretory epithelial cell.}, author={Dan R. Halm and Gerhard Rechkemmer and Robert A Schoumacher and Raymond A Frizzell}, journal={Comparative biochemistry and physiology. A, Comparative physiology}, year={1988}, volume={90 4}, pages={597-601} }