Biophysical evaluation of two red-shifted hypocrellin B derivatives as novel PDT agents.

Abstract

Two novel cyclohexane-1,2-diamino and N,N dimethyl amino-propyl substituted hypocrellin B derivatives, abbreviated as CHA2HB and DMAHB, respectively were synthesized. These derivatives exhibited enhanced absorption in phototherapeutic window. Photodynamic action of these derivatives, investigated using optical and electron spin resonance methods, depended… (More)
DOI: 10.1016/j.jphotobiol.2008.09.007

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