Biophysical clocks face a trade-off between internal and external noise resistance

@inproceedings{Pittayakanchit2018BiophysicalCF,
  title={Biophysical clocks face a trade-off between internal and external noise resistance},
  author={Weerapat Pittayakanchit and Zhiyue Lu and Justin Chew and Michael J Rust and Arvind Murugan},
  booktitle={eLife},
  year={2018}
}
Many organisms use free running circadian clocks to anticipate the day night cycle. However, others organisms use simple stimulus-response strategies ('hourglass clocks') and it is not clear when such strategies are sufficient or even preferable to free running clocks. Here, we find that free running clocks, such as those found in the cyanobacterium Synechococcus elongatus and humans, can efficiently project out light intensity fluctuations due to weather patterns ('external noise') by… CONTINUE READING

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