Biophysical characterization and structure of the Fab fragment from the NIST reference antibody, RM 8671.


Monoclonal antibody pharmaceuticals are the fastest-growing class of therapeutics, with a wide range of clinical applications. To assure their safety, these protein drugs must demonstrate highly consistent purity and stability. Key to these objectives is higher order structure measurements validated by calibration to reference materials. We describe… (More)
DOI: 10.1016/j.biologicals.2017.09.005


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