Biophysical characterization and functional consequences of a slowly inactivating potassium current in neostriatal neurons.

@article{Gabel1998BiophysicalCA,
  title={Biophysical characterization and functional consequences of a slowly inactivating potassium current in neostriatal neurons.},
  author={Lisa Gabel and Eric S. Nisenbaum},
  journal={Journal of neurophysiology},
  year={1998},
  volume={79 4},
  pages={1989-2002}
}
Neostriatal spiny projection neurons can display a pronounced delay in their transition to action potential discharge that is mediated by a slowly developing ramp depolarization. The possible contribution of a slowly inactivating A-type K+ current (IAs) to this delayed excitation was investigated by studying the biophysical and functional properties of IAs using whole cell voltage- and current-clamp recording from acutely isolated neostriatal neurons. Isolation of IAs from other voltage-gated… CONTINUE READING