Biophysical and molecular docking approaches for the investigation of biomolecular interactions between amphotericin B and bovine serum albumin.

@article{Raza2017BiophysicalAM,
  title={Biophysical and molecular docking approaches for the investigation of biomolecular interactions between amphotericin B and bovine serum albumin.},
  author={Muslim Raza and Aftab Ahmad and Feng Yue and Zahid Khan and Yang Jiang and Yun Wei and Saleem Raza and Wang He and Faheem Ullah Khan and Yuan Qipeng},
  journal={Journal of photochemistry and photobiology. B, Biology},
  year={2017},
  volume={170},
  pages={
          6-15
        }
}
Exogenous drug as an antidote to treat various infections get absorbed in the blood circulatory system of a human can directly contact with transporter proteins such as serum albumin. Therefore, for rational drug discovery, understanding the biomolecular interaction between drugs and protein is highly important. In this contribution, we describe the possible interactions between an antifungal drug Amphotericin B (AmB) and Bovine Serum Albumin (BSA) using multi-spectroscopic techniques and… CONTINUE READING