Biopharmaceutical benchmarks 2010

@article{Walsh2010BiopharmaceuticalB2,
  title={Biopharmaceutical benchmarks 2010},
  author={Gary Walsh},
  journal={Nature Biotechnology},
  year={2010},
  volume={28},
  pages={917-924}
}
  • G. Walsh
  • Published 1 September 2010
  • Biology
  • Nature Biotechnology
Over the past four years, several new types of experimental biologic treatment have received commercial registration, but the emergence of biosimilars represents the biggest shift in the biologic approval landscape. 

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  • P. Declerck
  • Biology
    Expert opinion on biological therapy
  • 2013
Taking into account the expected high development costs for biosimilar MAs, their use may well be superseded by alternative antibody formats and next-generation MAs.

Optional copayments on anti-cancer drugs

Patients may legitimately be asked to contribute to their costs of new cancer drugs, suggests Katelijne van de Vooren, Alessandro Curto, and Livio Garattini.

Technical hindrances in establishing biosimilarity - the final lap in the race

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This chapter will provide an overview of the discovery and development process for protein therapeutics with a primary focus on mAbs, and summarize the current status of the protein-based biologics field and discuss several future trends.

Analytical tools for characterizing biopharmaceuticals and the implications for biosimilars

The current state of the art in analytical technologies to assess three characteristics of protein biopharmaceuticals that regulatory authorities have identified as being important in development strategies for biosimilars: post-translational modifications, three-dimensional structures and protein aggregation are discussed.
...

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Biopharmaceutical benchmarks

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    Nature Biotechnology
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  • Biology, Medicine
    Nature Biotechnology
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