Bioorthogonal ligation in the spotlight.

  title={Bioorthogonal ligation in the spotlight.},
  author={Thomas Kurpiers and Henning D Mootz},
  journal={Angewandte Chemie},
  volume={48 10},
The light-induced formation of a covalent bond between an alkene group and a tetrazole moiety has been used for the selective labeling of proteins in vitro and in live cells. This bioorthogonal ligation initiated by brief irradiation with UV light leads to a fluorescent pyrazoline adduct (see scheme). 

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.