Bioorthogonal ligation in the spotlight.

@article{Kurpiers2009BioorthogonalLI,
  title={Bioorthogonal ligation in the spotlight.},
  author={Thomas Kurpiers and Henning D Mootz},
  journal={Angewandte Chemie},
  year={2009},
  volume={48 10},
  pages={1729-31}
}
The light-induced formation of a covalent bond between an alkene group and a tetrazole moiety has been used for the selective labeling of proteins in vitro and in live cells. This bioorthogonal ligation initiated by brief irradiation with UV light leads to a fluorescent pyrazoline adduct (see scheme). 

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