Biomolecular Characterization and Protein Sequences of the Campanian Hadrosaur B. canadensis

@article{Schweitzer2009BiomolecularCA,
  title={Biomolecular Characterization and Protein Sequences of the Campanian Hadrosaur B. canadensis},
  author={Mary Higby Schweitzer and Wenxia Zheng and Christopher Lee Organ and Recep Avci and Zhiyong Suo and Lisa M. Freimark and Valerie S. LeBleu and Mi Duncan and Matthew G. Vander Heiden and John M. Neveu and William S. Lane and John S. Cottrell and John R. Horner and Lewis C. Cantley and Raghu Kalluri and John M. Asara},
  journal={Science},
  year={2009},
  volume={324},
  pages={626 - 631}
}
The Birds and the Dinosaurs The extent to which primary tissues are preserved in ancient fossils remains controversial. Schweitzer et al. (p. 626; see the news story by Service) describe well-preserved tissues and primary collagen sequences from the femur of an 80-million-year-old hadrosaur. The fossil preserved structures resembling primary bone tissues and vessels. Both extracts and tissue pieces were analyzed in multiple laboratories by mass spectrometry, which revealed ancient collagen… Expand
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We used authentication tests developed for ancient DNA to evaluate claims by Asara et al. (Reports, 13 April 2007, p. 280) of collagen peptide sequences recovered from mastodon and Tyrannosaurus rexExpand
Interpreting Sequences from Mastodon and T. rex
TLDR
It is reported that collagen proteins from well-preserved ancient fossil bones from a 160,000- to 600,000 year-old mastodon and a 68-million-year-old T. rex can be extracted and sequenced by mass spectrometry. Expand
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Endogenous peptide sequences extracted from a 68-million-year-old Tyrannosaurus rex fossil bone and obtained by mass spectrometry have been shown to be statistically significant based on proteinExpand
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