Biomimetic tissues on a chip for drug discovery.

  title={Biomimetic tissues on a chip for drug discovery.},
  author={Amir M. Ghaemmaghami and Matthew J. Hancock and H. Michael Harrington and Hirokazu Kaji and Ali Khademhosseini},
  journal={Drug discovery today},
  volume={17 3-4},
Developing biologically relevant models of human tissues and organs is an important enabling step for disease modeling and drug discovery. Recent advances in tissue engineering, biomaterials and microfluidics have led to the development of microscale functional units of such models also referred to as 'organs on a chip'. In this review, we provide an overview of key enabling technologies and highlight the wealth of recent work regarding on-chip tissue models. In addition, we discuss the current… CONTINUE READING

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