Biomimetic nanofibrous gelatin/apatite composite scaffolds for bone tissue engineering.

@article{Liu2009BiomimeticNG,
  title={Biomimetic nanofibrous gelatin/apatite composite scaffolds for bone tissue engineering.},
  author={Xiaohua Liu and Laura Ashley Smith and Jiang Hu and Peter X Ma},
  journal={Biomaterials},
  year={2009},
  volume={30 12},
  pages={2252-8}
}
Mimicking certain features (e.g. nanoscale topography and biological cues) of natural extracellular matrix (ECM) is advantageous for the successful regeneration of damaged tissue. In this study, nanofibrous gelatin/apatite (NF-gelatin/apatite) composite scaffolds have been fabricated to mimic both the physical architecture and chemical composition of natural bone ECM. A thermally induced phase separation (TIPS) technique was developed to prepare nanofibrous gelatin (NF-gelatin) matrix. The NF… CONTINUE READING