Biomimetic collagen scaffolds for human bone cell growth and differentiation.

@article{Yang2004BiomimeticCS,
  title={Biomimetic collagen scaffolds for human bone cell growth and differentiation.},
  author={Xuebin B Yang and Rajendra S. Bhatnagar and Song Li and Richard O C Oreffo},
  journal={Tissue engineering},
  year={2004},
  volume={10 7-8},
  pages={1148-59}
}
Type I collagen provides a structural framework for connective tissues and plays a central role in the temporal cascade of events leading to the formation of new bone from progenitors. The aim of this study was to examine the ability of the cell-binding domain of type I collagen (P-15 peptide) to promote human bone marrow stromal cell adhesion, proliferation, and differentiation on three-dimensional scaffolds. Human bone marrow stromal cells were selected, expanded, and cultured on particulate… CONTINUE READING
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