Biomimetic Rebuilding of Multifunctional Red Blood Cells: Modular Design Using Functional Components.

  title={Biomimetic Rebuilding of Multifunctional Red Blood Cells: Modular Design Using Functional Components.},
  author={Jimin Guo and Jacob Ongudi Agola and Rita E. Serda and Stefan Franco and Qi Lei and Lu Wang and Joshua Minster and Jonas G. Croissant and Kimberly S. Butler and Wei Zhu and C. Jeffrey Brinker},
  journal={ACS nano},
The design and synthesis of artificial materials that mimic the structures, mechanical properties, and ultimately functionalities of biological cells remains a current holy grail of materials science. Here, based on a silica cell bioreplication approach, we report the design and construction of synthetic rebuilt red blood cells (RRBCs) that fully mimic the broad properties of native RBCs: size, biconcave shape, deformability, oxygen-carrying capacity, and long circulation time. Four successive… 

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