Biomedically relevant circuit-design strategies in mammalian synthetic biology

@inproceedings{Bacchus2013BiomedicallyRC,
  title={Biomedically relevant circuit-design strategies in mammalian synthetic biology},
  author={William Bacchus and Dominique Aubel and Martin Fussenegger},
  booktitle={Molecular systems biology},
  year={2013}
}
The development and progress in synthetic biology has been remarkable. Although still in its infancy, synthetic biology has achieved much during the past decade. Improvements in genetic circuit design have increased the potential for clinical applicability of synthetic biology research. What began as simple transcriptional gene switches has rapidly developed into a variety of complex regulatory circuits based on the transcriptional, translational and post-translational regulation. Instead of… CONTINUE READING
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