Biomedical three–dimensional holographic microimaging at visible, ultraviolet and X–ray wavelengths

@article{Boyer1996BiomedicalTH,
  title={Biomedical three–dimensional holographic microimaging at visible, ultraviolet and X–ray wavelengths},
  author={Keith Boyer and Johndale C. Solem and James W. Longworth and Alex B. Borisov and Charles K. Rhodes},
  journal={Nature Medicine},
  year={1996},
  volume={2},
  pages={939-941}
}
A new imaging technology is under advanced development that has several key advantages over conventional forms of microimaging performed with standard light microscopes, confocal light microscopes, and electron microscopes. The image created by this microscope possesses several unique features: It is intrinsically three-dimensional; it can be formed with very high contrast, a characteristic of the phase-sensitive nature of the recording; the information contained in the image is obtained in a… 
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  • 2008
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References

SHOWING 1-10 OF 12 REFERENCES
Fourier-transform holographic microscope.
TLDR
A holographic microscope with a spatial resolution approaching the diffraction limit and two unique capabilities that can collect three-dimensional information in a single pulse of light, avoiding specimen damage and bleaching is described.
Holography at x-ray wavelengths
We discuss alternative holographic techniques for imaging microscopic structures with a short-pulse, high intensity, high-quantum-energy laser. We find that Fresnel transform holography using a
X-Ray Biomicroholography
We discuss alternative techniques for microholography of biological specimens including requirements and constraints on the optical elements and recording media. We derive spatial and temporal
Microholography of Living Organisms
By using intense pulsed coherent x-ray sources that are currently under development, it will be possible to obtain magnified three-dimensional images of elementary biological structures in the living
X-Ray Holography of Microobjects
Possibilities of x-ray holography with the use of synchrotron radiation of modern electron storage rings are investigated. The required exposure time of a hologram and also that required of detected
Ultrahigh power compression for X-ray amplification: multiphoton cluster excitation combined with nonlinear channelled propagation
The ability to apply power densities controllably at or above vigorous thermonuclear levels (>1019 W cm-3) in materials is the basic issue for achieving efficient amplification of X-rays. Recent
Rethinking cell structure.
  • S. Penman
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1995
TLDR
Embedment-free electron microscopy gives clear, high-contrast micrographs of cell structure when combined with removal of obscuring material such as soluble proteins.
Optical Information Processing
This is the second volume on "Optical Information Processing" within the scope of the US-USSR Science Cooperation Program co- sponsored by the US National Science Foundation and the USSR Acad- emy of
...
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