Biomedical applications of high-performance liquid chromatography-mass spectrometry with continuous-flow fast atom bombardment.

@article{Millington1991BiomedicalAO,
  title={Biomedical applications of high-performance liquid chromatography-mass spectrometry with continuous-flow fast atom bombardment.},
  author={David S. Millington and Daniel Lee Norwood and Naoki Kodo and R Moore and Melinda Green and Judd Berman},
  journal={Journal of chromatography},
  year={1991},
  volume={562 1-2},
  pages={47-58}
}
This report describes the application of high-performance liquid chromatography combined with continuous-flow fast atom bombardment mass spectrometry to analytical problems in the biomedical laboratory. Applications include the compound-specific detection of diagnostic acylcarnitines in human urine, the separation and analysis of acyl-coenzyme A thioesters, and qualitative studies on complex mixtures of modified peptides (dansyl and dinitrophenyl derivatives). For each of these applications… CONTINUE READING