Biomechanical and Histomorphometric Colon Remodelling in STZ-Induced Diabetic Rats

@article{Zhao2008BiomechanicalAH,
  title={Biomechanical and Histomorphometric Colon Remodelling in STZ-Induced Diabetic Rats},
  author={Jingbo Zhao and Toshiya Nakaguchi and Hans Gregersen},
  journal={Digestive Diseases and Sciences},
  year={2008},
  volume={54},
  pages={1636-1642}
}
The histomorphologic and passive biomechanical properties were studied in the mid-colon of 16 non-diabetic and 20 streptozotocin (STZ)-induced diabetic rats (50 mg/kg STZ, ip). The diabetic rats were divided into groups living 4 and 8 weeks after the induction of diabetes (n = 10 for each group). The mechanical test was a ramp distension of fluid into the colon in vitro. The colon diameter and length were obtained from digitized images of the segments at pre-selected pressures and at the no… CONTINUE READING
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