Biomaterials in co-culture systems: towards optimizing tissue integration and cell signaling within scaffolds.

@article{Battiston2014BiomaterialsIC,
  title={Biomaterials in co-culture systems: towards optimizing tissue integration and cell signaling within scaffolds.},
  author={Kyle G. Battiston and Jane W C Cheung and Devika Jain and J Paul Santerre},
  journal={Biomaterials},
  year={2014},
  volume={35 15},
  pages={4465-76}
}
Most natural tissues consist of multi-cellular systems made up of two or more cell types. However, some of these tissues may not regenerate themselves following tissue injury or disease without some form of intervention, such as from the use of tissue engineered constructs. Recent studies have increasingly used co-cultures in tissue engineering applications as these systems better model the natural tissues, both physically and biologically. This review aims to identify the challenges of using… CONTINUE READING
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